UROGENITAL SYSTEM
Porsolt offers a range of models that address complications specific to, or are associated with, the urogenital system, including the assessment of renal function, bladder function and the genital system.
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UROGENITAL SYSTEM
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Bladder Function
Bladder function assessment includes a combination of tests that are used to examine the urinary system and how it is working.
EX-VIVO MODELS
Isolated bladder strip | Rat |
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Genital System
Genital system models evaluate potential effects of substances on the genital system.
IN VIVO MODELS
Isolated uterus | Rat |
Isolated vas deferens | Guinea-pig |
Penile erection | Rat |
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In Vitro Nephrology
In vitro nephrology can be studied in cellular models from multiple species.
IN VITRO MODELS
Calcium signaling | Multiple cellular models |
Cytolysis | Multiple cellular models |
Lysosomal activity | Multiple cellular models |
Mitochondrial membrane potential | Multiple cellular models |
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Renal Function
A renal function models evaluate kidney function in different conditions.
IN VIVO MODELS
Diuresis and urinary electrolytes | Mouse – Rat |
Unilateral ureteral obstruction-induced fibrosis mode | Rat |
HYPERTENSION MODELS
5/6 nephrectomy | Rat |
Chronic (2K1C) Goldblatt hypertension (high renin model) | Rat |
Chronic DOCA – salt hypertension (low renin model) | Rat |
BIOMARKER ASSAYS
PLATFORM | BIOMARKER | SPECIES (SAMPLE) |
---|---|---|
Histology (IHC-P) | Urothelium structure & thickness (E-Cadherin) | Rat |
Staining (paraffin slices) | Hematoxylin & Eosin, Sirius red, Masson’s trichrome,… | Multiple species & tissues |
Biochemical | Renal function (creatinin,urea, electrolytes, total protein, albumin) | Mouse, Rat (urine, serum, plasma) |
Glomerular filtration (creatinin clearance) | Mouse, Rat (serum, plasma) | |
Blood Urea Nitrogen (BUN) | Mouse, Rat (urine, serum, plasma) | |
CBA - ELISA - WB - IHC-PIHC-Fr - ICC - HTRF | Other targets upon request | Multiple species & biological specimens |
Porsolt
Z.A. de Glatigné
53940 Le Genest-Saint-Isle, France
Telephone +33 2 43 69 36 07
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