Porsolt offers a range of models that address complications specific to, or are associated with, the urogenital system, including the assessment of renal function, bladder function and the genital system.
Bladder function assessment includes a combination of tests that are used to examine the urinary system and how it is working.
|Isolated bladder strip||Rat|
Genital system models evaluate potential effects of substances on the genital system.
|Isolated vas deferens||Guinea-pig|
In vitro nephrology can be studied in cellular models from multiple species.
|Calcium signaling||Multiple cellular models|
|Cytolysis||Multiple cellular models|
|Lysosomal activity||Multiple cellular models|
|Mitochondrial membrane potential||Multiple cellular models|
A renal function models evaluate kidney function in different conditions.
|Diuresis and urinary electrolytes||Mouse – Rat|
|Unilateral ureteral obstruction-induced fibrosis mode||Rat|
|Chronic (2K1C) Goldblatt hypertension (high renin model)||Rat|
|Chronic DOCA – salt hypertension (low renin model)||Rat|
|Histology (IHC-P)||Urothelium structure & thickness (E-Cadherin)||Rat|
|Staining (paraffin slices)||Hematoxylin & Eosin, Sirius red, Masson’s trichrome,…||Multiple species & tissues|
|Biochemical||Renal function (creatinin,urea, electrolytes, total protein, albumin)||Mouse, Rat (urine, serum, plasma)|
|Glomerular filtration (creatinin clearance)||Mouse, Rat (serum, plasma)|
|Blood Urea Nitrogen (BUN)||Mouse, Rat (urine, serum, plasma)|
|CBA - ELISA - WB - IHC-PIHC-Fr - ICC - HTRF||Other targets upon request||Multiple species & biological specimens|