RESPIRATORY SYSTEM : Exploring Respiratory Indications with Expert Respiratory CRO Services

The intricate responses of the respiratory system to various compounds and therapies are at the heart of medical advancement. Porsolt, a leading respiratory CRO, offers a comprehensive range of models, and capabilities to scrutinize these effects. With a wealth of experience and a dedication to scientific excellence, we provide researchers with invaluable tools to assess compound efficacy and safety, ultimately contributing to the improvement of respiratory health worldwide.

Our Expertise in Respiratory CRO Services

Porsolt’s expertise shines through with our tailored respiratory preclinical CRO services. We understand that the complexities of the respiratory system demand a multifaceted approach. Leveraging diverse models and species, we meticulously examine airway function, asthma, cough, fibrosis, bronchospasm, and more. Our deep-rooted understanding of these models enables us to conduct comprehensive assessments, delivering accurate insights into the effects of compounds.




Isolated pulmonary artery Rat
Isolated trachea Rat – Guinea-pig
Airway function (whole body plethysmography) Mouse – Rat - Guinea-pig
Airway function in large animals Dogs
Airway function under hypercapnia (whole body plethysmography) Rat
Bleomycin-induced pulmonary fibrosis Mouse
Citric acid-induced cough Guinea-pig
Histamine bronchospasm Guinea-pig
LPS-induced pulmonary injury Mouse
Ovalbumin-induced asthma Guinea-pig
Staining (paraffin slices) Hepatic transporters (MRP-2, ZO-1,…) Multiple species & tissues
CBA TNF, IL-6, IL-1β , IL-10 and MCP-1 Mouse (BAL)
Biochemical MPO activity Mouse (whole lung)
Hematology WBC (White Blood Cell count): Neutrophils, Macrophages, Lymphocytes, Eosinophils,Basophils Mouse (BAL)
ELISA TNF, IL-6, IL-1β Mouse (BAL)
CBA–ELISA–WB–IHC-PIHC-Fr–ICC–HTRF Other targets upon request Multiple species & biological specimens

Central to unraveling the intricacies of the respiratory system is also our respiratory CRO expertise, capabilities, and technologies, in histology and bioanalysis. Our skilled team employs advanced histological and bioanalytical techniques to analyze tissue samples, unveiling microscopic and biochemical details that shed light on physiological responses. This meticulous approach allows us to identify cellular changes, tissue structure alterations, and disease markers, contributing to a profound understanding of respiratory health for patients.

A Collaborative Approach to Respiratory Research

At Porsolt, collaboration is paramount. Our respiratory CRO services can count on prestigious researchers to design studies tailored to their specific needs. Our team of dedicated scientists, researchers, and technicians works closely with clients to ensure that the chosen models and assessments align with the research objectives.

In our state-of-the-art respiratory system lab, cutting-edge technologies intersect with scientific curiosity. Equipped with the latest tools and methodologies, we delve into the intricacies of the respiratory diseases (asthma, pulmonary disease, cystic fibrosis, chronic sinusitis, etc.), providing robust data that drives progress.

Our experienced team of scientists has a deep understanding of the respiratory system and its complex interactions with other systems in the body. We offer a comprehensive range of respiratory preclinical CRO services, including : preclinical studies, histology of respiratory system as well as a state-of-the-art respiratory system lab.

As the landscape of respiratory health continues to evolve, Porsolt remains dedicated to shaping its trajectory. Through collaborative innovation, meticulous histological and bioanalysis assessments in our advanced histology laboratory, and an unwavering commitment to scientific excellence, we invite you to join us in exploring the frontiers of respiratory studies.

For more information about our Respiratory CRO services and how we can support your specific projects needs, please visit our website and contact us.


Z.A. de Glatigné
53940 Le Genest-Saint-Isle, France
Telephone +33 2 43 69 36 07

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