THROMBOSIS

Porsolt provides models for assessing the effects of compounds and potential therapies
on blood flow. These models can be used for investigating direct effects or
confounding and side effects of specific treatments on blood flow.

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thrombosis

THROMBOSIS

IN VITRO MODELS
Endothelial cell activation/ Drug-Induced Vascular Injury (DIVI) HUVECs cells
IN VIVO MODELS
Arterial thrombosis (FeCl2) Rat
Arterio-venous shunt (silk thread model) Rat
Bleeding time (anesthetized animal) Rat
Venous thrombosis (FeCl2) Rat
BIOMARKER ASSAYS
PLATFORM BIOMARKER SPECIES (SAMPLE)
Coagulation APTT (Activated Partial Thrombin Time) Multiple species
Prothrombin time Multiple species
Fibrinogen Multiple species
Hematology Complete Blood Count: - Red blood cells: hemoglobin, hematocrit, mean cell volume, mean cell hemoglobin concentration, platelets - White blood cells: lymphocytes, neutrophils, eosinophils, basophils, monocytes Multiple species
CBA - ELISA - WB - IHC-PIHC-Fr - ICC - HTRF Other targets upon request Multiple species & biological specimens

Porsolt

Z.A. de Glatigné
53940 Le Genest-Saint-Isle, France
Telephone +33 2 43 69 36 07

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