CARDIOVASCULAR SYSTEM : Unlock the potential of cardiovascular system research

As a leading provider with expertise in the cardiovascular system and many other areas, Porsolt offers unparalleled capabilities and resources to propel your research forward. Our comprehensive range of services includes cardiovascular system models, precise cardiovascular disease models, including  validated animal models and bioanalysis of cardiovascular conditions.

Recognizing the complexities inherent in cardiovascular research, Porsolt is equipped to address the challenges faced by researchers in evaluating the cardiovascular effects of their compounds. We provide an extensive selection of validated tests, designed for the precise assessment of key cardiovascular parameters. Our proficiency in cardiovascular histology and bioanalysis is particularly notable, enabling the meticulous examination of tissue samples. This facilitates the accurate identification of cellular anomalies and the detailed evaluation of disease markers.

Our team, comprising skilled scientists, researchers, and technicians, engages in close collaboration with clients to develop customized solutions that align with their specific research objectives. Utilizing state-of-the-art technologies, advanced methodologies, and stringent quality control protocols, we are committed to delivering reliable, reproducible results in the field of cardiovascular research.


Heart 3D


Arrhythmias & Cardiac Toxicity

Arrhythmias & Cardiac Toxicity

Search and Publications Catalog Contact Us Close

Arrhythmias & Cardiac Toxicity, as part of the cardiovascular system, encompass abnormal heart rhythms affecting blood pumping and heart muscle damage caused by toxins or medications, which results in impaired heart function.

Digoxin-induced ventricular arrhythmias (anesthetized animals) Guinea-pig
Torsades de Pointes arrhythmias (modified Carlsson model) Rabbit

Automatic Nervous System

The Autonomic Nervous System (ANS) regulates cardiovascular functions, including heart rate and blood pressure. The combination of our preclinical models, bioanalysis and histology capabilities, aids in gaining a better understanding of cardiovascular diseases.

Postural hypotension (anesthetized animals) Rat
Postural hypotension (telemetry) Rat

Cardiac Activity Recording

Cardiac Activity Recording

Search and Publications Catalog Contact Us Close

Cardiac Activity Recording, within the realm of the cardiovascular system, refers to the process of capturing and analyzing the electrical signals and mechanical activity of the heart. This technique allows researchers to study heart function, evaluate abnormalities, and gain insights into cardiovascular health.

Calcium assay iPSC-derived cardiomyocytes: iCell2®
hCav1.2 channel HEK 293 cells
hERG channel HEK 293 cells
hERG trafficking HEK 293 cells
hKir2.1 channel HEK 293 cells
hKir2.1 trafficking HEK 293 cells
hNav1.5 channel HEK 293 cells
Inositol triphosphate receptor channel function H9C2 cells
MEA assay iPSC-derived cardiomyocytes
Papillary muscle Guinea-pig
Purkinje fiber Rabbit – Dog
Spontaneously beating right atrium Guinea-pig – Rabbit
Stimulated left atrium Guinea-pig – Rabbit


Hemodynamics, within the context of the cardiovascular system, refers to the study of blood flow dynamics within the cardiovascular system. It focuses on the forces and pressures involved in the circulation of blood, including factors such as blood pressure, flow rate, and vascular resistance.



Arterial blood pressure, heart rate and ECG Rat – Guinea-pig
Bezold - Jarish reflex (capsaicin or 5-HT) Rat - Rabbit
Regional blood flow Rat
Systemic, cardiac, renal and pulmonary hemodynamics Dog – Mini-pig
Systemic and cardiac hemodynamics(cardiac denervated animal) Dog


Arterial blood pressure, heart rate ± ECG Mouse – Rat – Dog - Guinea-pig – Mini-pig
Left ventricular pressure, heart rate ± ECG Rat – Dog
Pulmonary arterial blood pressure, heart rate and ECG Dog
Right ventricular pressure and heart rate Rat


Hypertension, as part of the cardiovascular system, refers to a chronic medical condition characterized by high blood pressure. It involves increased force against arterial walls, leading to potential damage to blood vessels and organs.

Endothelial cell activation/Drug-Induced Vascular Injury HUVECs
5/6 nephrectomy rat
Arterial blood pressure and heart rate SH Rat
Arterial blood pressure and heart rate (telemetry) SH rat
Bile duct ligation-induced portal vein hypertension (telemetry) Rat
Chronic (2K1C) Goldblatt hypertension (high renin model) Rat
Chronic DOCA - salt hypertension(low renin model) Rat
Monocrotaline-induced pulmonary hypertension (anesthetized animals) Rat
Monocrotaline-induced pulmonary hypertension (telemetry) Rat

Isolated Vascular Beds

Isolated vascular beds refer to segments of blood vessels that can be separated and studied independently. They allow researchers to examine vascular responses, contractility, and other functional properties, providing insights into cardiovascular physiology and pathology.

Isolated mesenteric artery Dog
Isolated saphenous vein Rabbit – Dog
Isolated thoracic aorta Rat – Rabbit

By partnering with us, you gain access to a competent research lab equipped with the tools and knowledge to advance your cardiovascular research initiatives. Our deep understanding of the cardiovascular system enables us to uncover crucial insights into cardiovascular diseases, facilitating the development of innovative preclinical therapeutic areas and diagnostic approaches.

Contact us today to explore how our expertise in the cardiovascular system , our models, and comprehensive list of capabilities can accelerate your research and contribute to improving patient outcomes


Z.A. de Glatigné
53940 Le Genest-Saint-Isle, France
Telephone +33 2 43 69 36 07

Legal Notice

Any questions or concerns ?