News & Publications

On this page, you can find our publications in different disease areas and all the latest news and updates related to Porsolt.

Repiratory System

Although the whole body plethysmography for unrestrained animals is the most widely used method to assess the respiratory risk of new drugs …

Central Nervous System

Schizophrenia is characterized by three major symptom classes: positive symptoms, negative symptoms, and cognitive deficits. Classical antipsychotics (phenothiazines, thioxanthenes, and butyrophenones) are …

Cardio Vascular System

The protocols described in this unit are used to assess the effects of new chemical entities on arrhythmias in the guinea pig. …

Cardio Vascular System

The protocols described in this unit are used to assess the effects of new chemical entities on hypertension in conscious rats. In …

Central Nervous System

A novel bromide salt of the antidepressant bupropion (bupropion HBr) has recently been developed and approved for use in the United States. …

Central Nervous System

The behavioral despair test (BDT), also called the forced swim test, is an economic, reliable and sensitive test for the detection of …

Cardio Vascular System

Postural-change-induced (orthostatic) hypotension is defined as an excessive drop in arterial blood pressure occurring when moving toward an upright position. This side …

Central Nervous System

Depression is one of several disorders affecting mood, along with mania, hypomania, and bipolar disorders. The present chapter focuses on behavioral assessment …

gastro-intestinal system

The protocols described in this unit are designed to assess the effects of substances on intestinal transit and gastric emptying and to …

Central Nervous System

S100 proteins are small calcium-binding proteins interacting with numerous intra- and extra cellular targets involved in diverse physiological functions. In particular, S100 …

Porsolt

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53940 Le Genest-Saint-Isle, France
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