Tenascin-C promotes tumor cell migration and metastasis through integrin α9β1-mediated YAP inhibition. PORSOLT_Tenascin-C-promotes-tumor-cell-migration-and-metastasis-through-integrin-615379615381-mediated-YAP-inhibition.Download
In vitro electrophysiological safety studies have become an integral part of the drug development process since, in many instances, compound-induced QT prolongation has been associated with a direct block of…
SAFETY REGULATORY PACKAGE Porsolt’s broad expertise and years of preclinical pharmacology experience makes us the ideal partner to conduct your GLP Safety Pharmacology experiments. Porsolt offers safety studies in both…
MEDICAL DEVICES Porsolt’s vast array of models and technical capabilities that have been acquired and validated over many years, enable us to provide testing services for Medical Devices that follow…
UROGENITAL SYSTEM Porsolt offers a range of models that address complications specific to, or are associated with, the urogenital system, including the assessment of renal function, bladder function and the…
THROMBOSIS Porsolt provides models for assessing the effects of compounds and potential therapieson blood flow. These models can be used for investigating direct effects orconfounding and side effects of specific…
RESPIRATORY SYSTEM The effects of compounds and therapies on the respiratory system can be assessed using a variety of models, and species, with which Porsolt has extensive experience. These models…
PREDICTIVE TOXICITY Drug toxicity is one of the major reasons for drug attrition. Existing traditional methods do not have adequate in vitro predictability. Porsolt combines the most predictive cell models…