Cognition and Dementia in Brain Research
Porsolt continues its strong research record with a recently published paper in “Brain Research” on age-related cognitive deficits in mice.
Porsolt continues its strong research record with a recently published paper in “Brain Research” on age-related cognitive deficits in mice.
CENTRAL NERVOUS SYSTEM Porsolt offers models in all areas of psychopharmacology, epilepsy, sleep-wake, and neurodegenerative disorders. We are uniquely placed to offer a full range of CNS efficacy and safety…
Synergistic enhancing-memory effect of donepezil and S 47445, an AMPA positive allosteric modulator, in middle-aged and aged mice. PORSOLT_Synergistic-enhancing-memory-effect-of-donepezil-and-S-47445-an-AMPA-positive-allosteric-modulator-in-middle-aged-and-aged-mice.Download Keywords: AMPA receptors; Acetylcholine; Cognition; Aging; Alzheimer disease; Amnesia; Glutamate.
Parkinson's disease (PD) affects 1-2 per 1000 of the general population. PD prevalence is increasing with age and PD affects 1% of the population above 60 years. Most symptoms are…
The guidelines from different agencies do not include studies on cognitive functions as part of safety pharmacology. This is unfortunate as it seems important to verify that drugs entering into…