Central Nervous System

Interplay between 5-HT4 Receptors and GABAergic System within CA1 Hippocampal Synaptic Plasticity

• Post author:Maëliss Davy
• Post published:July 9, 2021
• Post category:Central Nervous System/Publications

…

Continue ReadingInterplay between 5-HT4 Receptors and GABAergic System within CA1 Hippocampal Synaptic Plasticity

Electrical amygdala kindling model

• Post author:Maëliss Davy
• Post published:March 29, 2021
• Post category:Central Nervous System/Publications

Porsolt continues to develop and improve preclinical models to meet the needs of the research community.

Continue ReadingElectrical amygdala kindling model

Cognition and Dementia in Brain Research

• Post author:Maëliss Davy
• Post published:November 16, 2020
• Post category:Central Nervous System/Publications

Porsolt continues its strong research record with a recently published paper in “Brain Research” on age-related cognitive deficits in mice.

Continue ReadingCognition and Dementia in Brain Research

Synergistic enhancing-memory effect of donepezil and S 47445, an AMPA positive allosteric modulator, in middle-aged and aged mice

• Post author:Maëliss Davy
• Post published:November 9, 2018
• Post category:Central Nervous System/Publications

…

Continue ReadingSynergistic enhancing-memory effect of donepezil and S 47445, an AMPA positive allosteric modulator, in middle-aged and aged mice

OBE022, an Oral and Selective Prostaglandin F2α Receptor Antagonist as an Effective and Safe Modality for the Treatment of Preterm Labor.

• Post author:Maëliss Davy
• Post published:July 19, 2018
• Post category:Central Nervous System/Publications

…

Continue ReadingOBE022, an Oral and Selective Prostaglandin F2α Receptor Antagonist as an Effective and Safe Modality for the Treatment of Preterm Labor.

HiPSC Parkinson’s disease Model

• Post author:Maëliss Davy
• Post published:January 9, 2018
• Post category:Central Nervous System/Publications

…

Continue ReadingHiPSC Parkinson’s disease Model

CRF1 receptor-deficiency increases cocaine reward

• Post author:Maëliss Davy
• Post published:August 20, 2017
• Post category:Central Nervous System/Publications

…

Continue ReadingCRF1 receptor-deficiency increases cocaine reward

Efficacy of anticonvulsant substances in the 6Hz seizure test

• Post author:Maëliss Davy
• Post published:May 5, 2017
• Post category:Central Nervous System/Publications

…

Continue ReadingEfficacy of anticonvulsant substances in the 6Hz seizure test

Effects of baclofen and raclopride on reinstatement of cocaine self-administration in the rat

• Post author:Maëliss Davy
• Post published:May 13, 2016
• Post category:Central Nervous System/Publications

…

Continue ReadingEffects of baclofen and raclopride on reinstatement of cocaine self-administration in the rat

CNS safety pharmacology: A focus on cognitive functions

• Post author:Maëliss Davy
• Post published:May 13, 2016
• Post category:Central Nervous System/Publications

…

Continue ReadingCNS safety pharmacology: A focus on cognitive functions