UROGENITAL SYSTEM

UROGENITAL SYSTEM

Porsolt offers a range of models that address complications specific to, or associated with, the urogenital system, including the assessment of renal function, bladder function, and the genital system.

CELL-BASED ASSAYS - NEPHROLOGY

Calcium signaling Multiple cellular models PF 3.33
Lysosomal activity Multiple cellular models PF 3.7
Mitochondrial membrane potential Multiple cellular models PF 3.3
Cytolisis Multiple cellular models PF 3.4
Cell-Based assays - Learn More on Fluofarma' portfolio

RENAL FUNCTION

IN VIVO
Diuresis and urinary electrolytes Mouse - Rat REN 1
Renal function (Inulin and PAH clearance) Rat REN 2

HYPERTENSION MODELS

IN VIVO
5/6 nephrectomy Rat REN 3
Chronic DOCA - salt hypertension (low renin model) Rat CV 2.3
Chronic (2K1C) Goldblatt hypertension (high renin model) Rat CV 2.5
Renal Function - Learn More

BLADDER FUNCTION

IN VITRO
Isovolumetric rhythmic bladder contractions (anesthetized animal) Rat UG 2
Bladder function and micturition reflex (cystometry) (anesthetized rat or conscious dog) Rat - Dog UG 3
Overactive bladder (acetic acid infusion) (cystometry) (anesthetized animal) Rat - Dog UG 4
Cyclophosphamide-induced cystitis (anesthetized animal) Rat UG 6
EX VIVO
Isolated bladder strip Rat VSM 4
Bladder Function - Learn More

GENITAL SYSTEM

IN VIVO
Penile erection Rat UG 1
Intracavernous pressure (anesthetized animal) Rat UG 5
EX VIVO
Isolated uterus Rat VSM 3
Isolated vas deferens Guinea-pig VSM 5
Genital System - Learn More