TARGETING METASTASIS

ONCOLOGY

Oncology is an area that commands a larger proportion of the research world's resources. Porsolt is now able to provide services using its Oncology in vitro capabilities and expertise.

TARGETING METASTASIS

To target the tumor invasion and metastasis, Porsolt has qualified several models to provide in vitro screnning and efficacy testing.

- 2D migration model

- 3D invasion model

- Intravenous metastasis models : Syngenic (mouse cells) or Xenograft (human cells)

- Orthotopic models

- Resection models

OUR PORTFOLIO

  • IN VITRO
Kinetic analysis of the wound healing Multiple 2D cellular models
Invasion assay for screening and efficacy studies Multiple 3D cellular models
  • IN OVO

NEW!

Experimental metastasis CAM Assay (screening – 3R approach)

Chicken eggs

In development

  • IN VIVO
Experimental lung metastasis syngeneic
model of breast cancer
4T1 cells ONC 1.1
Experimental lung metastasis syngeneic
model of colon cancer
CT26.WT cells ONC 1.2

NEW!

Experimental lung metastasis xenograft
model of breast cancer

MDA-MB-231 cells

Mouse

ONC 8.1

NEW!

Experimental lung metastasis xenograft
model of colon cancer

HCT-116/HCT-8

Mouse

In development