ONCOLOGY
Oncology is an area that commands a larger proportion of the research world's resources. Porsolt is now able to provide services using its Oncology in vitro capabilities and expertise.
Porsolt maintains a panel of human cancer cell lines to establish in vitro tumor models in 2D or 3D. Isolated from tissue-specific tumors and grown in vitro, cancer cell lines are particularly suited for anti-cancer drug screening.
(Please contact us if you want us to test your compounds in a specific model: several cell lines are available for each tumor type, and our panel is regularly augmented with new cell lines)
LYMPHATIC SYSTEM | Burkitt's lymphoma Diffuse large B cell lymphoma Follicular lymphoma Hodgkin's lymphoma Non-Hodgkin's B cell lymphoma |
IMMUNE SYSTEM | Acute T cell leukemia Acute lymphoblastic leukemia Monocyte leukemia Promyelocytic leukemia |
MAMMARY SYSTEM | Breast carcinoma |
DIGESTIVE SYSTEM CARCINOMAS |
Colorectal carcinoma Hepatoma Pancreas carcinoma |
UROGENITAL SYSTEM | Bladder carcinoma Cervical adenocarcinoma Prostate carcinoma |
BRAIN & ENDOCRINE SYSTEM TUMORS |
Glioblastoma Neuroblastoma Pheochromocytoma Pituitary adenoma |
SKIN AND SOFT TISSUES CANCERS |
Fibrosarcoma Melanoma |
LUNG CANCER | Alveolar basal epithelial lung Adenocarcinoma |
Porsolt has applied its proprietary biosensor technology (DAPS) to a number of cell lines within this panel, thus allowing the reagent-less quantification of caspase, gamma-secretase and calpain activity by high-throughput flow cytometry.
>>> Learn more about our drug discovery services in oncology, or more generally, about our preclinical services.