OBESITY & METABOLIC DISORDERS

OBESITY & METABOLIC DISORDERS

Obesity and metabolism related disorders are key therapeutic areas that have attracted global attention over recent years. Porsolt has in place a comprehensive range of models for obesity, impaired glucose tolerance, and diabetes to assist with the development of novel therapeutic agents for the treatment and reduction of risk factors associated with metabolic diseases.

METABOLIC DISORDERS

i.v. glucose tolerance test (IVGTT) Rat MET 1
Oral glucose tolerance test (OGTT) (in normal or pathologic animals) Mouse - Rat MET 12
Insulin tolerance test (ITT) Mouse - Rat MET 2
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OBESITY

Fast-induced feeding (over 4 hours) Mouse MET 13
Acute 24-hr feeding Rat MET 14
Food/water intake and body weight gain (3-hr schedule-fed over 10 days) Rat MET 6
Food/water intake and body weight gain in Zucker, DIO, db/db,… (24-hr over 28 days) Mouse - Rat MET 7
Oral glucose tolerance test (OGTT) in DIO, db/db,… Mouse - Rat MET 12
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DIABETES

Type I Alloxan induced diabetes model Rat MET 17
Type I STZ – induced diabetes Mouse - Rat MET 16
Type II HFD / STZ – induced diabetes Rat MET 15
Type I & II Genetical models (ZDF/NOD/db/db…) Mouse - Rat MET 12
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