DERMATOLOGY

DERMATOLOGY

Dermatological diseases represent a major health problem due to the substantial patient population that is affected. Psoriasis, Allergic Contact Dermatitis (ACD) and Atopical Dermatitis (Allergic or Irritant Contact Dermatitis) are the major skin diseases of immunological origin.

IN VITRO
Cytolysis Multiple cellular models PF 3.4
Cell cycle Multiple cellular models PF 3.8
Cell proliferation Multiple cellular models PF 3.9
Cell Migration wound healing Multiple cellular models PF 3.14
Autophagy (LC3B) HeLa cells PF 3.17
NF kB activation Multiple cellular models PF 3.23
cAMP quantification Multiple cellular models PF 3.34
Mitochondrial Membrane Potential Multiple cellular models PF 3.3
Glycerol release/lipolysis Adipocytes PF 7.1
Lipid, intracellular accumulation: neutral lipids Multiple cellular models PF 3.29
Lipid, intracellular accumulation: phospholipids Multiple cellular models PF 3.30
TNFalpha -induced cytotoxicity L929 cell line PF 4.1
H2O2-induced oxidative damage Keratinocytes PF 4.2

NEW !

Total collagen formation

Normal human
dermal fibroblasts

PF 4.3

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IN VIVO
Imiquimod-induced psoriasis-like skin inflammation Mouse DER 1
Allergic Contact Dermatitis Pig  DER 2
Pruritogens-induced scratching behavior Mouse - Rat DER 3