IN VIVO NEUROSCIENCE SERVICES

CENTRAL NERVOUS SYSTEM

Porsolt offers models in all areas of psychopharmacology, epilepsy, sleep-wake, and neurodegenerative disorders. We are uniquely placed to offer a full range of CNS efficacy and safety pharmacology assessments, from basic models and regulatory tests, through the evaluation of abuse and dependence liability and proconvulsant risk using EEG.

IN VIVO NEUROSCIENCE SERVICES

To demonstrate the in vivo efficacy and mechanism of action of a neuroactive compound, Porsolt combines functional behavioral assessments with neurobiological measurements in brain tissues. Our automated approach to brain histology enables quantitative and multiplexed biomarkers studies with subcellular resolution, either in brain tissue sections or tissue microarrays.

IN VIVO MODELS OF NEUROLOGICAL DISORDERS

According to your need, we select animal models of specific nervous system diseases, either based on animal genetic modification, pharmacological treatment, xeno- or allo- grafts strategies:

>  Rodent disease models (Parkinson’s disease, Huntington's disease, Alzheimer's disease , …)



OUR APPROACH / CASE STUDY

COGNITIVE & BEHAVIORAL NEUROSCIENCE TESTS

Thanks to privileged partnerships with private companies and academic institutions, Porsolt can perform a range of gold standard tests to assess the in vivo efficacy of neuroactive compounds.