Isolated vascular beds

CARDIOVASCULAR SYSTEM

Porsolt has an extensive portfolio of cardiovascular procedures, ranging from standard cardiovascular telemetry studies for safety evaluation, to pathophysiological models for specific therapeutic areas. Porsolt also possesses considerable expertise with in vitro models, providing clients with a comprehensive assessment of all aspects of cardiovascular function.

Isolated vascular beds

Tissue pharmacology assays

In vitro tissue pharmacology assays may serve to extend results obtained from radioligand binding assays. Tissues are isolated from smooth muscles of the cardiovascular, respiratory, gastrointestinal or urogenital tracts. Agonist or antagonist activities of the test substances are evaluated on quiescent or pre-contracted preparations.