HIGH-TROUGHPUT FLOW CYTOMETRY

We hold a specific expertise in the multiplexed detection of intracellular markers by automated flow cytometry. Therefore, in addition to supporting drug discovery through high-throughput flow cytometry screens, we offer to quantify biomarkers in blood samples in the context of in vivo studies and clinical trials, to assess target hitting, perform pharmacokinetic studies or stratify patients.

> High-throughput: up to 40 000 events acquired per second

> Multiplexing: up to 18 parameters measured simultaneously

> Single-cell analysis: immunophenotyping enables the analysis of intracellular events in specific cell subpopulations

> Robust measurements, with accurate Z’ factors

> Predictive cellular models tailored to your need, based on cell lines, primary cell cultures or stem cells

> Proprietary DAP technology: for reagentless quantification of caspase, calpain or γ-secretase activity by flow cytometry

> Key expertise in intracellular markers (phosphoproteins, signaling pathways, ...) for cell-based screening and biomarker detection in blood samples